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How Does CBD Work With Ibuprofen?

CBD and Ibuprofen are known as good options for pain relief. As for now ibuprofen may be a more popular choice for pain killers, but CBD is gaining in popularity as a natural pain relief solution with other health benefits. Before we find out whether CBD and ibuprofen can work together or not, let's get to know more about ibuprofen first.

  • Ibuprofen, belongs to a Non-Steroidal Anti-inflammatory Drugs (NSAIDs).

  • Ibuprofen are sold under brands like Nurofen, Nurofen, Advil or Motrin worldwide.

  • It was introduced in 1961.

  • Ibuprofen is not only a painkiller, but it can relieve inflammation and also is an anti-fever agent.

  • Ibuprofen works by stopping the production of prostaglandins, which is a substance found in your body that helps stimulate pain, inflammation and fever.

  • Ibuprofen blocks the enzymes for the production of prostaglandins therefore it reduces pain, inflammation and inflammation.

  • Ibuprofen should be treated as a short-term solution for pain management.

  • Using ibuprofen for long term puts you at risk for ulcer, upset stomach, high blood pressure, gastrointestinal bleeding, kidney disease or cardiovascular risk.

  • Painkillers like ibuprofen may be addictive and lead to dependency.

  • Cannabidiol or CBD on the other hand is not intoxicating and will not cause you to feel "high."

  • CBD is a natural product extracted from hemp.and cannabis plants and is completely non-addictive.

  • People have been using CBD for a very long time and the first uses of CBD can be dated back to 2727 B.C. China.

  • CBD has multiple health benefits that includes pain relief, reduce Inflammation, improve sleep, treat insomnia, reduce stress and anxiety, treat depression and mental health issues, reduce nausea and motion sickness, have neuroprotective properties and can reduce tremors and epilepsy symptoms.

  • Scientists believe that CBD interacts with the Endocannabinoid System (ECS), a complex network of receptors and neurotransmitters along your body.

  • The ECS regulates various essential bodily functions and one of them is pain perception.

  • CBD is believed to interact with the two main receptors, CB1 and CB2 receptors. CB1 receptors are found in the central nervous system while CB2 receptors are mostly found in the peripheral nervous system and the immune system.

  • By interacting with the receptors, CBD can modify pain signals and reduce Inflammation which will result in creating pain-relieving effects.

  • Another theory is that CBD interacts with the serotonin and vanilloid receptors found in the neurotransmitters which could create analgesic properties and are essential to pain relieving.

It seems that both ibuprofen and CBD have unique pain relieving and anti-inflammatory properties, but can they both work together?

It's best to first understand that CBD may interact with other medications.

CBD when taken with other medications can increase or decrease the effects of medication. CBD interacts with other medications because it affects the enzymes in the liver especially the cytochrome P450 enzymes. P450 enzymes play a crucial role in metabolizing pharmaceutical drugs. Therefore CBD can play a role in how much your body can process medications.

To read more about what medications that should not be taken with CBD click here:

Can CBD and Ibuprofen be used together then?

We recommend:

The time and dosage of CBD and Ibuprofen should be separated to avoid negative impacts.

You should never take ibuprofen with an empty stomach, but you can take CBD anytime of the day especially the ones made from CBD isolate like Mellow 900mg CBD Oil that is free from THC and will not cause you to feel high.

CBD made from full spectrum like Mellow 1,800 mg CBD Oil comes with high potency CBD and even though it contains cannabinoids like THC, but it's for medicinal purposes and will not cause you to feel high is a great choice too.

Consult your doctor for the right dosage and recommendation for using CBD with other medications.

If you are looking for a high quality CBD product then Mellow Organic is the right choice for you: Mellow Organic now has three very fine CBD products: Mellow CBD Oil made from CBD Isolate, Mellow Full Spectrum CBD Oil and Mellow CBD Soothing Balm. For more information please visit or feel free to contact our Mellow Organic team anytime.

Written by Vivek Roachthavilit


Mellow Organic

Center For Advancing Health

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