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New neurological research points out that CBD alleviates THC impact on the brain

Updated: Jul 31, 2023

New neurological research points out that CBD alleviates THC impact on the brain

There are hundreds of cannabinoids (chemical compound found in the cannabis plant) and two of the most well known compounds are Cannabidiol (CBD) and Delta-9-tetrahydrocannabinol (THC). Both CBD and THC have similar medicinal therapeutic properties like treating insomnia, improving sleep reducing stress and anxiety, pain management, anti-inflammation, antidepressants or mood enhancers. Both of these components interact with the endocannabinoid system that helps regulate mood, appetite, pain management, sleep and appetite. CBD and THC are considered safe and have very little side effects. They are non-addictive and have no withdrawal symptoms. The big difference is CBD does not have psychoactive effects so it will not cause you to feel intoxicated or "high". THC in a high level may cause you to feel high.

A recent finding published in Journal of Psychopharmacology has pointed out that CBD may alleviate the effects of THC. Cannabis strains with a higher content of CBD is less harmful. There are evidence that high strength cannabis which normally contains high amount of THC and very little CBD may be more dangerous and lead to addiction and have negative effects on mental disorders such as psychosis.

Researchers were interested in studying the effects of cannabinoids with the functioning of the striatum. Striatum is a part of the brain that controls movement. It is also involved with reward-related information processing of the brain. The striatum is said to be part of addiction and psychosis symptoms. A better understanding of how cannabis can interact with striatum would be very important in understanding cannabis as an alternative for health treatment.

Findings from the research shows that:

1. THC and CBD have opposing effects

2. When using THC without CBD it causes disruptive effects on the functional connectivity of the striatum

3. CBD without THC increases striatum connectivity

4. Using cannabis strain with THC and CBD decreases striatum connectivity, but less than using THC alone.

5. Different types of cannabis strain have different effects on the brain

6. A balanced cannabis strain will be more productive to the brain's function

7. CBD by itself seems to have minimal effects to the brain making it an ideal choice for therapy treatment

Matthew Wall who was part of the research team had commented that “Cannabis is transitioning to legal or semi-legal status in a lot of places around the world, and that means more people will potentially be exposed to cannabinoids,” he added. “Understanding the effects of different cannabinoids is a vital effort to ensure that people have the best information about the cannabis they use and can make well-informed choices.”

A healthy lifestyle along with natural supplements like CBD can make a difference in your health and well being. For more information on Mellow Organic and our lab tested and organic CBD products please visit or

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