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What is CBDa and Its Role In Full Spectrum CBD?

What is CBDa and Its Role In Full Spectrum CBD?

Cannabidiolic Acid or CBDa is the main phytocannabinoid found in fibers and cannabis sativiate plants (seed-oil hemps).

Unfortunately, in the past more focus was on cannabinoids like CBD and THC while overlooking cannabinoids like CBDa, THCa, CBG or CBN. But scientists have found that CBDa may have health benefits that could be advantageous to us and we will find out what they are today.

The popularity and good reception of cannabis and medical marijuana has led to scientists wanting to learn and experimenting more with the therapeutic properties of CBD and cannabis.

If you are a seasoned CBD user and you have been using CBD products made from Broad Spectrum or Full Spectrum CBD then chances are high that you have consumed CBDa without being aware that it was already in your full spectrum CBD.

CBDa is available in raw cannabis and trace amounts can be found in full spectrum CBD like Mellow Full Spectrum CBD Oil 1,800 mg of CBD.

CBDa is the precursor of CBD. CBDa is found in cannabis flowers.

Acidic cannabinoids like CBDa or THCa will decarboxylates (break down) when exposed to heat.

We know that THC has psychoactive properties that can interact with CB1 and CB2 receptors in the Endocannabinoid System along your body. The endocannabinoid system helps to regulate mood, appetite, sleep, behavior, digestion, pain, stress and anxiety. While CBD, the non-psychoactive cannabinoid have multiple healing benefits to help promote the entourage effect such as pain relief, anti-inflammation, reduce of stress and anxiety, promote sleep, treat insomnia, reduce nausea and motion sickness.

CBDa and THCa are not considered to be pharmacologically active as it does not interact with the endocannabinoid system like the way processed cannabinoids like CBD or THC does. Because of this there has been more research on THC and CBD.

But things are changing. In 2008, researchers have noticed that the molecular structures of CBDa is very similar to NSAIDS which are nonsteroidal anti-inflammatory drugs. They noticed that they have the same COX-2 inhibitors that help NSAID to treat inflammation.

CBDa is believed to be a very effective treatment for nausea or anxiety. A study in 2013 in Canada found that CBDa is a thousand times more powerful than CBD when treating nausea or anxiety. CBDa binds with some particular serotonin receptors that are responsible for treating anti-nausea and anti-anxiety when used with low dosage of anti-nausea drugs for chemotherapy treatment.

Researchers have found that CBDa has a potential to treat cancer. They have found that CBDa in raw cannabis was able to stop migration of cancer cells or Metastasis in breast cancer in science lab. More research on animals and human test labs are needed.

CBDa like some cannabinoids like CBD, CBG or CBN, is also showing that it has potential for anti-viral to combat bacteria infection.

Scientists have noticed that CBDa interacts with certain serotonin receptors that is directly involved with wellness and mood showing potential for helping treat mental disorders.

More research is needed as we know very little about CBDa and research in this cannabinoid is still in its infancy state, but from what we know everything looks very promising.

If you are looking for CBDa along with CBD, THC and other cannabinoids along with terpenes and flavonoids then it's time you try Mellow Organic's Mellow Full Spectrum CBD Oil.

Mellow Organic is a good choice if you are looking for high quality lab-tested premium CBD products. Let us introduce you to our line of products:

Mellow CBD Oil is our CBD Isolate option that comes in 900 mg CBD available in Natural and Orange flavors. One bottle is 30ml. Mellow CBD Oil is perfect for beginners or people that just want CBD without other cannabinoids.

Mellow Full Spectrum CBD Oil comes with 1,800 mg of CBD with THC and other cannabinoids, terpenes and flavonoids for the greatest entourage effect. Available in a 30ml bottle.

Mellow CBD Soothing Balm is our vanilla scented CBD-infused topical for people looking to relieve pain, muscle soreness and reduce stress and anxiety. Also, great for joint pain. Our balm comes in 50 grams tin.

For more information about Mellow Organic find us at

Written by

Vivek Roachthavilit

Drug Metabolism and Disposition

National Institutes of Health


Analytical Cannabis


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